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| AFRH CONFERENCE 2021 ABSTRACTS |
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| Year : 2021 | Volume
: 6
| Issue : 1 | Page : 22 |
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AFRH Conference 2021 Abstracts
| Date of Web Publication | 05-Sep-2022 |
Correspondence Address:
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2468-8452.355650
How to cite this article:
. AFRH Conference 2021 Abstracts. Afr J Infertil Assist Concept 2021;6:22 |
Abstract 1 Intrauterine Adhesion Is a Major Pathology Detected at Hysteroscopy among Black African Women: A 15-Year Study
Abayomi Bolaji Ajayi, Victor Dayo Ajayi, Bamgboye M Afolabi
Abstract
Objective: The objective of the study was to ascertain the anthropometric and gynecologic profiles of Black African women with abnormal hysteroscopic findings.
Materials and Methods: This was a retrospective study in which case records of 1631 black African women who presented for assisted reproductive technology (ART) from 2003 to 2018 were examined. Analysis was conducted with STATA 13 statistical software.
Results: Anthropometric profile indicates that the means of age (years) and of body mass index (kg/m2) were 38.7 (6.4) and 28.1 (5.3), respectively. Those who never had uterine surgery (n = 276, 16.9%) were significantly younger (t-test = 5.10, P value = 0.0000001) than those who had had uterine surgery (n = 1,355, 83.1%). The incidence of uterine polyps, endocervical polyps, fibroid, and intrauterine adhesion (IUA) among those who have had uterine surgery was 12.4%, 1.5%, 14.4%, and 28.0%, respectively, compared with 20.2%, 2.8%, 15.3%, and 8.7% among those who had never had uterine surgery. In general, subfertile women who had undergone various uterine surgeries (n = 200, 14.8%) were 4.7 times more likely to present with IUA (χ² = 51.6, P value = 0.0000001, odds ratio [OR] = 4.73, 95% confidence interval [CI] = 2.99–7.50) and 1.89 times more likely to present with polyps compared with women who had not undergone any uterine surgery (χ² = 14.55, P value = 0.0001, OR = 1.89, 95% CI = 1.36–2.64).
Conclusions: IUA was most prevalent among subfertile women presenting for ART, especially among those who had undergone multiple previous uterine surgical procedures such as D&C, C/S, and myomectomy. These findings underscore the importance of the past history of uterine surgical procedures and of hysteroscopy among those presenting for fertility management.
Keywords:
Fibroids, hysteroscopy, intrauterine adhesions, polyps, uterine surgical procedures
Abstract 2 Challenges with a Provision of Assisted Reproductive Technology (ART) in a Public Institution in Nigeria: The University of Port Harcourt (UPTH) Experience
Solomon Nyeche, Kinikanwo Innocent Green, Vaduneme Oriji, Preye Owen Fiebai, John Ikimalo
Abstract
Objective: The objective of the study was to highlight challenges with a provision of assisted reproductive technology (ART) at the University of Port Harcourt (UPTH).
Materials and Methods: We carried out a retrospective review of in vitro fertilization treatment cycles from January 2017 to December 2020.
Results: The Assisted Conception Unit at the UPTH commenced treatment cycles 7 years after its initiation because of bureaucratic bottlenecks. A total of 50 cycles were carried out in eight batches in a 3-year period. Fourteen couples were treated in 2017 in three batches, 20 in 2018 in three batches, and 16 in 2019 in two batches. Autologous cycles were initiated in 34 couples, whereas 16 were oocyte recipients. The cancellation rate was 16% (four autologous cycles and four donor cycles, all occasioned by a poor response to stimulation). The long gonadotropin-releasing hormone analog protocol with downregulation on day 21 was used for stimulation. The first three batches were treated with a relatively cheap brand of human menopausal gonadotropin (hMG), but this was changed to recombinant follicle stimulation hormone and highly purified hMG due to a poor response. The mean age of the female partners was 36.6 ± 5.9 years (range = 29–49 years). The modal number of embryos transferred in 34 clients was three; recipients of less than three embryos had only two embryos (seven clients) and one embryo (seven clients). The clinical pregnancy rate was 16% per initiated cycle. Challenges encountered included a lack of a resident embryologist, industrial unrest, and inability of clients to pay for the service.
Conclusion: Nigerian public institutions that plan to provide ART services from the experience of others can learn lessons and avoid challenges faced by others.
Keywords:
Assisted reproduction, challenges, Nigeria, public institution
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